Association of Methylentetraydrofolate Reductase (MTHFR) 677 C &gt; T gene polymorphism and homocysteine levels in psoriasis vulgaris patients from Malaysia: a case-control study

Cheok Liew, Siaw; Dasgupta, Esha; Fung Wong, Shew; Lee, Nagarajah; Safdar, Najeeb; Jamil, Adawiyah

doi:10.1186/1475-2891-11-1

Public

Association of Methylentetraydrofolate Reductase (MTHFR) 677 C > T gene polymorphism and homocysteine levels in psoriasis vulgaris patients from Malaysia: a case-control study

Published in Nutrition Journal • Jan 5, 2012

Authors:

Siaw Cheok Liew

Esha Dasgupta

Shew Fung Wong

Abstract

BACKGROUND: The methylenetetrahydrofolate reductase (MTHFR) enzyme catalyzes the reduction of 5, 10-methylenetetrahydrofolate to 5-methyltetrahydrofolate and methyl donors. The methyl donors are required for the conversion of homocysteine to methionine. Mutation of MTHFR 677 C > T disrupts its therm...

Subject

Methylenetetrahydrofolate reductase

Psoriasis

Homocysteine

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