Epigenetic Silencing of Interferon-κ in Human Papillomavirus Type 16–Positive Cells

Rincón‐Orozco, Bladimiro; Halec, Gordana; Rosenberger, Simone; Muschik, Dorothea; Nindl, Ingo; Bachmann, Anastasia; Maria Ritter, Tina; Dondog, Bolormaa; Ly, Regina; X. Bosch, Franz; Zawatzky, Rainer; Rösl, Frank

doi:10.1158/0008-5472.can-09-0550

Public

Epigenetic Silencing of Interferon-κ in Human Papillomavirus Type 16–Positive Cells

Published in Cancer Research • Nov 4, 2009

Authors:

Bladimiro Rincón‐Orozco

Gordana Halec

Simone Rosenberger

Abstract

We have investigated interferon-kappa (IFN-kappa) regulation in the context of human papillomavirus (HPV)-induced carcinogenesis using primary human foreskin keratinocytes (HFK), immortalized HFKs encoding individual oncoproteins of HPV16 (E6, E7, and E6/E7), and cervical carcinoma cells. Here, IFN-...

Subject

Biology

Interferon

Cancer research

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