Global sequence variation in the histidine-rich proteins 2 and 3 of Plasmodium falciparum: implications for the performance of malaria rapid diagnostic tests

Baker, Joanne; Ho, Mei‐Fong; Pelecanos, Anita; L. Gatton, Michelle; Chen, Nanhua; Abdullah, Salim; Albertini, Audrey; Ariey, Frédéric; W. Barnwell, John; Bell, David; Cunningham, Jane; Djallé, Djibrine; F. Echeverry, Diego; Gamboa, Dionicia; Hii, Jeffery; Phone Kyaw, Myat; Luchavez, Jennifer; Membi, Christopher; Ménard, Didier; Murillo, Claribel; Nhem, Sina; Ogutu, Bernhards; Onyor, Pamela; Oyibo, Wellington; Qing Wang, Shan; McCarthy, James; Cheng, Qin

doi:10.1186/1475-2875-9-129

Public

Global sequence variation in the histidine-rich proteins 2 and 3 of Plasmodium falciparum: implications for the performance of malaria rapid diagnostic tests

Published in Malaria Journal • May 17, 2010

Authors:

Joanne Baker

Mei‐Fong Ho

Anita Pelecanos

Abstract

BACKGROUND: Accurate diagnosis is essential for prompt and appropriate treatment of malaria. While rapid diagnostic tests (RDTs) offer great potential to improve malaria diagnosis, the sensitivity of RDTs has been reported to be highly variable. One possible factor contributing to variable test perf...

Subject

Plasmodium falciparum

Malaria

Biology

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