Evaluation of a 30-Gene Paclitaxel, Fluorouracil, Doxorubicin, and Cyclophosphamide Chemotherapy Response Predictor in a Multicenter Randomized Trial in Breast Cancer

Tabchy, Adel; Valero, Vicente; Vidaurre, Tatiana; Lluch, Aňa; Gómez, Henry; Martín, Miguel; Qi, Yuan; Javier Barajas-Figueroa, Luis; Souchon, Eduardo; Coutant, Charles; D. Doimi, Franco; K. Ibrahim, Nuhad; Gong, Yun; N. Hortobágyi, Gabriel; R. Hess, Kenneth; Fraser Symmans, W.; Pusztai, Lajos

doi:10.1158/1078-0432.ccr-10-1265

Public

Evaluation of a 30-Gene Paclitaxel, Fluorouracil, Doxorubicin, and Cyclophosphamide Chemotherapy Response Predictor in a Multicenter Randomized Trial in Breast Cancer

Published in Clinical Cancer Research • Sep 9, 2010

Authors:

Adel Tabchy

Vicente Valero

Tatiana Vidaurre

Abstract

PURPOSE: We examined in a prospective, randomized, international clinical trial the performance of a previously defined 30-gene predictor (DLDA-30) of pathologic complete response (pCR) to preoperative weekly paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide (T/FAC) chemotherapy, and as...

Subject

Cyclophosphamide

Medicine

Chemotherapy

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