Glucosamine, Chondroitin Sulfate, and the Two in Combination for Painful Knee Osteoarthritis

O. Clegg, Daniel; J. Reda, Domenic; L. Harris, Crystal; Klein, Marguerite; R. O’Dell, James; Hooper, Michele; Bradley, John; O. Bingham, Clifton; H. Weisman, Michael; G. Jackson, Christopher; E. Lane, Nancy; J. Cush, John; W. Moreland, Larry; Ralph Schumacher, H.; V. Oddis, Chester; Wolfe, Frederick; A. Molitor, Jerry; E. Yocum, David; J. Schnitzer, Thomas; E. Furst, Daniel; D. Sawitzke, Allen; Shi, Helen; D. Brandt, Kenneth; W. Moskowitz, Roland; James Williams, H.

doi:10.1056/nejmoa052771

Public

Glucosamine, Chondroitin Sulfate, and the Two in Combination for Painful Knee Osteoarthritis

Published in New England Journal of Medicine • Feb 22, 2006

Authors:

Daniel O. Clegg

Domenic J. Reda

Crystal L. Harris

Abstract

BACKGROUND: Glucosamine and chondroitin sulfate are used to treat osteoarthritis. The multicenter, double-blind, placebo- and celecoxib-controlled Glucosamine/chondroitin Arthritis Intervention Trial (GAIT) evaluated their efficacy and safety as a treatment for knee pain from osteoarthritis. METHODS...

Subject

Osteoarthritis

Medicine

Chondroitin sulfate

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