Association Between Chromosome 9p21 Variants and the Ankle-Brachial Index Identified by a Meta-Analysis of 21 Genome-Wide Association Studies

M. Murabito, Joanne; C. White, Charles; Kavousi, Maryam; V. Sun, Yan; F. Feitosa, Mary; Nambi, Vijay; Lamina, Claudia; Schillert, Arne; Coassin, Stefan; C. Bis, Joshua; Broer, Linda; C. Crawford, Dana; Franceschini, Nora; Frikke‐Schmidt, Ruth; Haun, Margot; Holewijn, Suzanne; E. Huffman, Jennifer; Hwang, Shih-Jen; Kiechl, Stefan; Kollerits, Barbara; E. Montasser, May; M. Nolte, Ilja; E. Rudock, Megan; Senft, Andrea; Teumer, Alexander; van der Harst, Pim; Vitart, Véronique; L. Waite, Lindsay; R. Wood, Andrew; L. Wassel, Christina; Absher, Devin; Allison, Matthew; Amin, Najaf; M. Arnold, Alice; W. Asselbergs, Folkert; S. Aulchenko, Yurii; Bandinelli, Stefania; Barbalić, Maja; Boban, Mladen; Brown‐Gentry, Kristin; Couper, David; H. Criqui, Michael; Dehghan, Abbas; den Heijer, Martin; Dieplinger, Benjamin; Ding, Jingzhong; Dörr, Marcus; Espinola–Klein, Christine; B. Felix, Stephan; Ferrucci, Luigi; R. Folsom, Aaron; Fraedrich, Gustav; Gibson, Quince; Goodloe, Robert; Gunjača, Grgo; Haltmayer, Meinhard; Heiss, Gerardo; Hofman, Albert; Kieback, Arne; A. Kiemeney, Lambertus; Kolčić, Ivana; J. Kullo, Iftikhar; B. Kritchevsky, Stephen; J. Lackner, Karl; Li, Xiaohui; Lieb, Wolfgang; Lohman, Kurt; Meisinger, Christa; Melzer, David; R. Mohler, Emile; Mudnić, Ivana; Mueller, Thomas; Navis, Gerjan; Oberhollenzer, Friedrich; W. Olin, Jeffrey; O’Connell, Jeff; J. O’Donnell, Christopher; Palmas, Walter; W.J.H. Penninx, Brenda; Petersmann, Astrid; Polašek, Ozren; M. Psaty, Bruce; Rantner, Barbara; Rice, Kenneth; Rivadeneira, Fernando; I. Rotter, Jerome; Seldenrijk, Adrie; Stadler, Marietta; Summerer, Monika; Tanaka, Toshiko; Tybjærg‐Hansen, Anne; G. Uitterlinden, André; H. van Gilst, Wiek; H. Vermeulen, Sita; H. Wild, Sarah; S. Wild, Philipp; Willeit, Johann; Zeller, Tanja; Zemunik, Tatijana; Zgaga, Lina; L. Assimes, Themistocles; Blankenberg, Stefan; Boerwinkle, Eric; Campbell, Harry; P. Cooke, John; de Graaf, Jacqueline; Herrington, David; L. R. Kardia, Sharon; D. Mitchell, Braxton; Murray, Anna; Münzel, Thomas; B. Newman, Anne; A. Oostra, Ben; Rudan, Igor; R. Shuldiner, Alan; Snieder, Harold; M. van Duijn, Cornelia; Völker, Uwe; F. Wright, Alan; Wichmann, H.‐Erich; F. Wilson, James; C.M. Witteman, Jacqueline; Liu, Ching‐Ti; Hayward, Caroline; B. Borecki, Ingrid; Ziegler, Andreas; E. North, Kari; Adrienne Cupples, L.; Kronenberg, Florian

doi:10.1161/circgenetics.111.961292

Public

Association Between Chromosome 9p21 Variants and the Ankle-Brachial Index Identified by a Meta-Analysis of 21 Genome-Wide Association Studies

Published in Circulation Cardiovascular Genetics • Dec 24, 2011

Authors:

Joanne M. Murabito

Charles C. White

Maryam Kavousi

Abstract

BACKGROUND: Genetic determinants of peripheral arterial disease (PAD) remain largely unknown. To identify genetic variants associated with the ankle-brachial index (ABI), a noninvasive measure of PAD, we conducted a meta-analysis of genome-wide association study data from 21 population-based cohorts...

Subject

Genome-wide association study

Meta-analysis

Genetic association

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