A conformational heparan sulfate binding site essential to infectivity overlaps with the conserved hepatitis B virus A-determinant

Sureau, Camille; Salisse, Jessica

doi:10.1002/hep.26125

Public

A conformational heparan sulfate binding site essential to infectivity overlaps with the conserved hepatitis B virus A-determinant

Published in Hepatology • Nov 14, 2012

Authors:

Camille Sureau

Jessica Salisse

Abstract

UNLABELLED: Two determinants of infectivity have been identified in the hepatitis B virus (HBV) envelope proteins: a pre-S1 receptor-binding site and an uncharacterized determinant in the antigenic loop (AGL), which is structurally related to the antigenic a-determinant. Infection would proceed thro...

Subject

Avidity

Infectivity

Hepatitis B virus

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