Bleeding complications with the P2Y12 receptor antagonists clopidogrel and ticagrelor in the PLATelet inhibition and patient Outcomes (PLATO) trial

C. Becker, Richard; Bassand, Jean‐Pierre; Budaj, Andrzej; Wojdyla, Daniel; James, Stefan; H. Cornel, Jan; French, J.; Held, Claes; Horrow, Jay; Husted, Steen; López-Sendón, José; Lassila, Riitta; W. Mahaffey, Kenneth; F. Storey, Robert; Harrington, Richard; Wallentin, L.

doi:10.1093/eurheartj/ehr422

Public

Bleeding complications with the P2Y12 receptor antagonists clopidogrel and ticagrelor in the PLATelet inhibition and patient Outcomes (PLATO) trial

Published in European Heart Journal • Nov 16, 2011

Authors:

Richard C. Becker

Jean‐Pierre Bassand

Andrzej Budaj

Abstract

AIMS More intense platelet-directed therapy for acute coronary syndrome (ACS) may increase bleeding risk. The aim of the current analysis was to determine the rate, clinical impact, and predictors of major and fatal bleeding complications in the PLATO study. METHODS AND RESULTS PLATO was a randomize...

Subject

Medicine

Ticagrelor

Clopidogrel

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