Systematic analysis of microRNA expression of RNA extracted from fresh frozen and formalin-fixed paraffin-embedded samples

Xi, Yaguang; Nakajima, Go; Gavin, Elaine; G. Morris, Chris; Kudo, Kenji; Hayashi, Kazuhiko; Ju, Jingfang

doi:10.1261/rna.642907

Public

Systematic analysis of microRNA expression of RNA extracted from fresh frozen and formalin-fixed paraffin-embedded samples

Published in RNA • Aug 13, 2007

Authors:

Yaguang Xi

Go Nakajima

Elaine Gavin

Abstract

microRNAs (miRNAs) are noncoding small RNAs that regulate gene expression at the translational level by mainly interacting with 3' UTRs of their target mRNAs. Archived formalin-fixed paraffin-embedded (FFPE) specimens represent excellent resources for biomarker discovery. Currently there is a lack o...

Subject

Biology

microRNA

Molecular biology

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