Pioglitazone for Diabetes Prevention in Impaired Glucose Tolerance

A. DeFronzo, Ralph; Tripathy, Devjit; C. Schwenke, Dawn; Banerji, MaryAnn; A. Bray, George; A. Buchanan, Thomas; Clement, Stephen; R. Henry, Robert; N. Hodis, Howard; E. Kitabchi, Abbas; J. Mack, Wendy; Mudaliar, Sunder; E. Ratner, Robert; Williams, Ken; B. Stentz, Frankie; Musi, Nicolas; D. Reaven, Peter

doi:10.1056/nejmoa1010949

Public

Pioglitazone for Diabetes Prevention in Impaired Glucose Tolerance

Published in New England Journal of Medicine • Mar 23, 2011

Authors:

Ralph A. DeFronzo

Devjit Tripathy

Dawn C. Schwenke

Abstract

BACKGROUND: Impaired glucose tolerance is associated with increased rates of cardiovascular disease and conversion to type 2 diabetes mellitus. Interventions that may prevent or delay such occurrences are of great clinical importance. METHODS: We conducted a randomized, double-blind, placebo-control...

Subject

Pioglitazone

Medicine

Placebo

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