Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis

E. Hogan, Andrew; Tobin, Anne‐Marie; Ahern, Tomás; Corrigan, M.; Gaoatswe, Gadinthsware; Jackson, Ruaidhrí; O’Reilly, Vincent; Lynch, Lydia; G. Doherty, Derek; N. Moynagh, Paul; Kirby, Brian; O’Connell, Jean; O’Shea, Donal

doi:10.1007/s00125-011-2232-3

Public

Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis

Published in Diabetologia • Jul 8, 2011

Authors:

Andrew E. Hogan

Anne‐Marie Tobin

Tomás Ahern

Abstract

AIMS/HYPOTHESIS: The innate immune cells, invariant natural killer T cells (iNKT cells), are implicated in the pathogenesis of psoriasis, an inflammatory condition associated with obesity and other metabolic diseases, such as diabetes and dyslipidaemia. We observed an improvement in psoriasis severi...

Subject

Human physiology

Psoriasis

Diabetes mellitus

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