Association of HLA-BFNx011502 allele and carbamazepine-induced<i>Stevens-Johnson syndrome</i>among Indians

Mehta, TimirY; Prajapati, LaxmanM; Mittal, Bharti; G. Joshi, Chaitanya; Sheth, JayeshJ; Patel, DineshB; Dave, DinkarM; Goyal, RameshK

doi:10.4103/0378-6323.57718

Public

Association of HLA-BFNx011502 allele and carbamazepine-inducedStevens-Johnson syndromeamong Indians

Published in Indian Journal of Dermatology Venereology and Leprology • Jan 1, 2009

Authors:

TimirY Mehta

LaxmanM Prajapati

Bharti Mittal

Abstract

BACKGROUND: Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis are severe cutaneous reactions caused by certain drugs, including antiepileptic carbamazepine. A strong association has been reported between human leucocyte antigen (HLA)-B*1502 and carbamazepine-induced SJS in Han Chinese pa...

Subject

Carbamazepine

Toxic epidermal necrolysis

Genotyping

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