Smooth muscle cell matrix metalloproteinase production is stimulated via alpha(v)beta(3) integrin.

MP, Bendeck; C, Irvin; M, Reidy; L, Smith; D, Mulholland; M, Horton; CM, Giachelli

doi:10.1161/01.atv.20.6.1467

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Smooth muscle cell matrix metalloproteinase production is stimulated via alpha(v)beta(3) integrin.

Shared by NobleBlocks on Jun 1, 2000 • 12:00 AM UTC

Authors:

Bendeck MP

Irvin C

Reidy M

Abstract

This study tests the hypothesis that alpha(v)beta(3) integrin receptors play a critical role in smooth muscle cell (SMC) migration after arterial injury and facilitate migration through the upregulation of matrix metalloproteinase (MMP) activity. We showed that beta(3) integrin mRNA was upregulated ...

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