Two-Generation Reproductive Toxicity Study of Dietary Bisphenol A in CD-1 (Swiss) Mice

W. Tyl, Rochelle; Myers, Christina; C. Marr, Melissa; S. Sloan, Carol; P. Castillo, Nora; Michael Veselica, M.; Curtis Seely, John; S. Dimond, Stephen; Philip Miller, J.; N. Shiotsuka, Ronald; Beyer, D.; G. Hentges, Steven; M. Waechter, John

doi:10.1093/toxsci/kfn084

Public

Two-Generation Reproductive Toxicity Study of Dietary Bisphenol A in CD-1 (Swiss) Mice

Published in Toxicological Sciences • Apr 29, 2008

Authors:

Rochelle W. Tyl

Christina Myers

Melissa C. Marr

Abstract

Dietary bisphenol A (BPA) was evaluated in a mouse two-generation study at 0, 0.018, 0.18, 1.8, 30, 300, or 3500 ppm (0, 0.003, 0.03, 0.3, 5, 50, or 600 mg BPA/kg/day, 28 per sex per group). A concurrent positive control group of dietary 17beta-estradiol (0.5 ppm; 28 per sex) confirmed the sensitivi...

Subject

Reproductive toxicity

Toxicity

Bisphenol A

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