Antitrypanosomal and Antileishmanial Activities of Flavonoids and Their Analogues: In Vitro, In Vivo, Structure-Activity Relationship, and Quantitative Structure-Activity Relationship Studies

Taşdemir, Deniz; Kaiser, Marcel; Brun, Reto; Yardley, Vanessa; J. Schmidt, Thomas; Tosun, Fâtma; Rüedi, Peter

doi:10.1128/aac.50.4.1352-1364.2006

Public

Antitrypanosomal and Antileishmanial Activities of Flavonoids and Their Analogues: In Vitro, In Vivo, Structure-Activity Relationship, and Quantitative Structure-Activity Relationship Studies

Published in Antimicrobial Agents and Chemotherapy • Mar 28, 2006

Authors:

Deniz Taşdemir

Marcel Kaiser

Reto Brun

Abstract

Trypanosomiasis and leishmaniasis are important parasitic diseases affecting millions of people in Africa, Asia, and South America. In a previous study, we identified several flavonoid glycosides as antiprotozoal principles from a Turkish plant. Here we surveyed a large set of flavonoid aglycones an...

Subject

Antiprotozoal

Trypanosoma brucei rhodesiense

In vivo

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!