Randomized, Controlled Trial of Irinotecan Plus Infusional, Bolus, or Oral Fluoropyrimidines in First-Line Treatment of Metastatic Colorectal Cancer: Results From the BICC-C Study

S. Fuchs, Charles; L. Marshall, John; P. Mitchell, Edith; Wierzbicki, Rafal; Ganju, Vinod; Jeffery, Mark; J. Schulz, Joseph; Richards, Donald; Soufi‐Mahjoubi, Raoudha; Wang, Benjamin; Barrueco, José

doi:10.1200/jco.2007.11.3357

Public

Randomized, Controlled Trial of Irinotecan Plus Infusional, Bolus, or Oral Fluoropyrimidines in First-Line Treatment of Metastatic Colorectal Cancer: Results From the BICC-C Study

Published in Journal of Clinical Oncology • Oct 18, 2007

Authors:

Charles S. Fuchs

John L. Marshall

Edith P. Mitchell

Abstract

PURPOSE: This phase III study compared the safety and efficacy of the following three different irinotecan-containing regimens in the first-line treatment of metastatic colorectal cancer: irinotecan plus infusional fluorouracil (FU)/leucovorin (LV) (FOLFIRI), irinotecan plus bolus FU/LV (mIFL), and ...

Subject

FOLFIRI

Medicine

Irinotecan

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