Dopamine Controls Persistence of Long-Term Memory Storage

I. Rossato, Janine; R. Bevilaqua, Lia; Izquierdo, Iván; H. Medina, Jorge; Cammarota, Martı́n

doi:10.1126/science.1172545

Public

Dopamine Controls Persistence of Long-Term Memory Storage

Published in Science • Aug 20, 2009

Authors:

Janine I. Rossato

Lia R. Bevilaqua

Iván Izquierdo

Abstract

The paradigmatic feature of long-term memory (LTM) is its persistence. However, little is known about the mechanisms that make some LTMs last longer than others. In rats, a long-lasting fear LTM vanished rapidly when the D1 dopamine receptor antagonist SCH23390 was injected into the dorsal hippocamp...

Subject

Ventral tegmental area

Dopaminergic

Dopamine

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