The Role of the α 2 -Adrenoceptor Agonist Dexmedetomidine in Postsurgical Sedation in the Intensive Care Unit

Dexmedetomidine was evaluated for sedation of 401 post-surgical patients in this double-blind, randomized, placebo-controlled, multicenter trial. Dexmedetomidine or saline was started on arrival in the intensive care unit (ICU) (1.0 mcg/kg for 10 minutes), then titrated at 0.2 to 0.7 mcg/kg/h to eff... View More