The Role of the α
                    <sub>2</sub>
                    -Adrenoceptor Agonist Dexmedetomidine in Postsurgical Sedation in the Intensive Care Unit

Martin, Eike; Ramsay, Graham; Mantz, Jean; T. John Sum-Ping, S.

doi:10.1177/0885066602239122

Public

The Role of the α 2 -Adrenoceptor Agonist Dexmedetomidine in Postsurgical Sedation in the Intensive Care Unit

Shared by NobleBlocks on Jan 1, 2003 • 12:00 AM UTC

Authors:

Eike Martin

Graham Ramsay

Jean Mantz

Abstract

Dexmedetomidine was evaluated for sedation of 401 postsurgical patients in this double-blind, randomized, placebocontrolled, multicenter trial. Dexmedetomidine or saline was started on arrival in the intensive care unit (ICU) (1.0 mcg/kg for 10 minutes), then titrated at 0.2 to 0.7 mcg/kg/h to effec...

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