Rituximab versus Azathioprine for Maintenance in ANCA-Associated Vasculitis

Guillevin, Loı̈c; Pagnoux, Christian; Karras, Alexandre; Khouatra, C.; Aumaître, O.; Cohen, Pascal; Maurier, F.; Decaux, Olivier; Ninet, J.; Gobert, P.; Quéméneur, T.; Blanchard‐Delaunay, Claire; Godmer, Pascal; Puéchal, Xavier; Carron, Pierre‐Louis; Hatron, Pierre‐Yves; Limal, Nicolas; Hamidou, M.; Ducret, M.; Daugas, Éric; Papo, T.; Bonnotte, Bernard; Mahr, Alfred; Ravaud, Philippe; Mouthon, Luc

doi:10.1056/nejmoa1404231

Public

Rituximab versus Azathioprine for Maintenance in ANCA-Associated Vasculitis

Published in New England Journal of Medicine • Nov 5, 2014

Authors:

Loı̈c Guillevin

Christian Pagnoux

Alexandre Karras

Abstract

BACKGROUND: The combination of cyclophosphamide and glucocorticoids leads to remission in most patients with antineutrophil cytoplasm antibody (ANCA)-associated vasculitides. However, even when patients receive maintenance treatment with azathioprine or methotrexate, the relapse rate remains high. R...

Subject

Rituximab

Medicine

Azathioprine

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