Distinct Roles of NR2A and NR2B Cytoplasmic Tails in Long-Term Potentiation

A. Foster, Kelly; McLaughlin, Nathan; Edbauer, Dieter; A. Phillips, Marnie; D. Bolton, Andrew; Constantine‐Paton, Martha; Sheng, Morgan

doi:10.1523/jneurosci.4022-09.2010

Public

Distinct Roles of NR2A and NR2B Cytoplasmic Tails in Long-Term Potentiation

Published in Journal of Neuroscience • Feb 17, 2010

Authors:

Kelly A. Foster

Nathan McLaughlin

Dieter Edbauer

Abstract

NMDA receptors (NMDARs) are critical mediators of activity-dependent synaptic plasticity, but the differential roles of NR2A- versus NR2B-containing NMDARs have been controversial. Here, we investigate the roles of NR2A and NR2B in long-term potentiation (LTP) in organotypic hippocampal slice cultur...

Subject

Long-term potentiation

NMDA receptor

LTP induction

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