A Biologic Definition of Burkitt's Lymphoma from Transcriptional and Genomic Profiling

Hummel, Michael; Bentink, Stefan; Berger, Hilmar; Klapper, Wolfram; Weßendorf, Swen; F.E. Barth, Thomas; Bernd, Heinz‐Wolfram; Cogliatti, Sergio; Dierlamm, Judith; C. Feller, Alfred; Hansmann, Martin‐Leo; Haralambieva, Eugenia; Harder, Lana; Hasenclever, Dirk; W.M. Kühn, Michael; Lenze, Dido; Lichter, Peter; I. Martín‐Subero, José; Mӧller, Peter; Müller-Hermelink, Hans-Konrad; Ott, German; Parwaresch, Reza; Pott, Christiane; Rosenwald, Andreas; Rosołowski, Maciej; Schwäenen, Carsten; Stürzenhofecker, Benjamin; Szczepanowski, Monika; Trautmann, Heiko; Wacker, Hans‐Heinrich; Spang, Rainer; Loeffler, Markus; Trümper, Lorenz; Stein, Harald; Siebert, Reiner

doi:10.1056/nejmoa055351

Public

A Biologic Definition of Burkitt's Lymphoma from Transcriptional and Genomic Profiling

Published in New England Journal of Medicine • Jun 7, 2006

Authors:

Michael Hummel

Stefan Bentink

Hilmar Berger

Abstract

BACKGROUND: The distinction between Burkitt's lymphoma and diffuse large-B-cell lymphoma is unclear. We used transcriptional and genomic profiling to define Burkitt's lymphoma more precisely and to distinguish subgroups in other types of mature aggressive B-cell lymphomas. METHODS: We performed gene...

Subject

Lymphoma

Burkitt's lymphoma

Fluorescence in situ hybridization

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