Centrally infused atrial natriuretic polypeptide attenuates exaggerated salt appetite in spontaneously hypertensive rats.

Itoh, Hiroshi; Nakao, Kazuhiko; Katsuura, Goro; Morii, Narito; Shiono, Satoshi; Sakamoto, Makoto; Sugawara, Akira; Yamada, Takayuki; Saito, Yoshihiko; Matsushita, Akira

doi:10.1161/01.res.59.3.342

Public

Centrally infused atrial natriuretic polypeptide attenuates exaggerated salt appetite in spontaneously hypertensive rats.

Published in Circulation Research • Sep 1, 1986

Authors:

Hiroshi Itoh

Kazuhiko Nakao

Goro Katsuura

Abstract

We have previously shown that atrial natriuretic polypeptide is present in the brain with the highest concentration in the hypothalamus and septum and that intracerebroventricular injection of atrial natriuretic polypeptide inhibits water drinking induced by centrally injected angiotensin II or 24-h...

Subject

Internal medicine

Endocrinology

Thirst

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