FOLFIRI Followed by FOLFOX6 or the Reverse Sequence in Advanced Colorectal Cancer: A Randomized GERCOR Study

Tournigand, Christophe; André, Thierry; Achille, Emmanuel; Lledo, Gérard; Flesh, Michel; Méry-Mignard, D.; Quinaux, Emmanuel; Couteau, C.; Buyse, Marc; Ganem, G.; Landi, Bruno; Colin, Philippe; Louvet, Christophe; de Gramont, Aimery

doi:10.1200/jco.2004.05.113

Public

FOLFIRI Followed by FOLFOX6 or the Reverse Sequence in Advanced Colorectal Cancer: A Randomized GERCOR Study

Published in Journal of Clinical Oncology • Dec 8, 2003

Authors:

Christophe Tournigand

Thierry André

Emmanuel Achille

Abstract

PURPOSE: In metastatic colorectal cancer, phase III studies have demonstrated the superiority of fluorouracil (FU) with leucovorin (LV) in combination with irinotecan or oxaliplatin over FU + LV alone. This phase III study investigated two sequences: folinic acid, FU, and irinotecan (FOLFIRI) follow...

Subject

Folinic acid

Irinotecan

FOLFIRI

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