Briakinumab for Treatment of Crohnʼs Disease

Panaccione, Remo; J. Sandborn, William; L. Gordon, Glenn; D. Lee, Scott; Safdi, Alan; Sedghi, Shahriar; G. Feagan, Brian; B. Hanauer, Stephen; Reinisch, Walter; F. Valentine, John; Huang, Bidan; Carcereri, Roberto

doi:10.1097/mib.0000000000000366

Public

Briakinumab for Treatment of Crohnʼs Disease

Published in Inflammatory Bowel Diseases • Apr 1, 2015

Authors:

Remo Panaccione

William J. Sandborn

Glenn L. Gordon

Abstract

BACKGROUND: This study assessed the efficacy and safety of briakinumab, a human anti-IL-12/23p40 monoclonal antibody, compared with placebo for the induction and maintenance of remission in patients with moderately to severely active Crohn's disease. METHODS: In this phase 2b, multicenter, double-bl...

Subject

Tolerability

Medicine

Placebo

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