The Influence of Finasteride on the Development of Prostate Cancer

M. Thompson, Ian; J. Goodman, Phyllis; M. Tangen, Catherine; Scott Lucia, M.; J. Miller, Gary; G. Ford, Leslie; M. Lieber, Michael; Duane Cespedes, R.; N. Atkins, James; M. Lippman, Scott; M. Carlin, Susie; Ryan, Anne; M. Szczepanek, Connie; J. Crowley, John; A. Coltman, Charles

doi:10.1056/nejmoa030660

Public

The Influence of Finasteride on the Development of Prostate Cancer

Published in New England Journal of Medicine • Jul 16, 2003

Authors:

Ian M. Thompson

Phyllis J. Goodman

Catherine M. Tangen

Abstract

BACKGROUND: Androgens are involved in the development of prostate cancer. Finasteride, an inhibitor of 5alpha-reductase, inhibits the conversion of testosterone to dihydrotestosterone, the primary androgen in the prostate, and may reduce the risk of prostate cancer. METHODS: In the Prostate Cancer P...

Subject

Finasteride

Medicine

Rectal examination

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