Forkhead Transcription Factor FKHR-L1 Modulates Cytokine-Dependent Transcriptional Regulation of p27 <sup>KIP1</sup>

F. Dijkers, Pascale; H. Medema, René; Pals, Cornelieke; Banerji, Lolita; Shaun B. Thomas, N.; W.‐F. Lam, Eric; Burgering, Boudewijn; A. M. Raaijmakers, Jan; J. Lammers, Jan‐Willem; Koenderman, Leo; J. Coffer, Paul

doi:10.1128/mcb.20.24.9138-9148.2000

Public

Forkhead Transcription Factor FKHR-L1 Modulates Cytokine-Dependent Transcriptional Regulation of p27 KIP1

Published in Molecular and Cellular Biology • Dec 1, 2000

Authors:

Pascale F. Dijkers

René H. Medema

Cornelieke Pals

Abstract

Interleukin-3 (IL-3), IL-5, and granulocyte-macrophage colony-stimulating factor regulate the survival, proliferation, and differentiation of hematopoietic lineages. Phosphatidylinositol 3-kinase (PI3K) has been implicated in the regulation of these processes. Here we investigate the molecular mecha...

Subject

Biology

Transcription factor

Ectopic expression

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