The Key Role of Anaplerosis and Cataplerosis for Citric Acid Cycle Function

E. Owen, Oliver; C. Kalhan, Satish; W. Hanson, Richard

doi:10.1074/jbc.r200006200

Public

The Key Role of Anaplerosis and Cataplerosis for Citric Acid Cycle Function

Published in Journal of Biological Chemistry • Aug 1, 2002

Authors:

Oliver E. Owen

Satish C. Kalhan

Richard W. Hanson

Abstract

tricarboxylic acid cycle phosphoenolpyruvate carboxykinase phosphoenolpyruvate The oxidation of acetyl-CoA to CO2by the TCA1 cycle is the central process in energy metabolism. However, the TCA cycle also functions in biosynthetic pathways in which intermediates leave the cycle to be converted primar...

Subject

Citric acid cycle

Phosphoenolpyruvate carboxykinase

Gluconeogenesis

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