Cerebral folate receptor autoantibodies in autism spectrum disorder.
Published in Molecular psychiatry • Mar 1, 2013
Authors:,,
R E Frye
J M Sequeira
E V Quadros
Abstract
Cerebral folate deficiency (CFD) syndrome is a neurodevelopmental disorder typically caused by folate receptor autoantibodies (FRAs) that interfere with folate transport across the blood-brain barrier. Autism spectrum disorders (ASDs) and improvements in ASD symptoms with leucovorin (folinic acid) t...
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