The Developmentally Regulated<i>alb1</i>Gene of<i>Aspergillus fumigatus</i>: Its Role in Modulation of Conidial Morphology and Virulence

Tsai, Huei‐Fung; C. Chang, Yun; G. Washburn, Ronald; H. Wheeler, Michael; J. Kwon‐Chung, Kyung

doi:10.1128/jb.180.12.3031-3038.1998

Public

The Developmentally Regulatedalb1Gene ofAspergillus fumigatus: Its Role in Modulation of Conidial Morphology and Virulence

Published in Journal of Bacteriology • Jun 15, 1998

Authors:

Huei‐Fung Tsai

Yun C. Chang

Ronald G. Washburn

Abstract

Aspergillus fumigatus, an important opportunistic pathogen which commonly affects neutropenic patients, produces conidia with a bluish-green color. We identified a gene, alb1, which is required for conidial pigmentation. The alb1 gene encodes a putative polyketide synthase, and disruption of alb1 re...

Subject

Biology

Conidiation

Virulence

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