TLR5 stop codon polymorphism is associated with invasive aspergillosis after allogeneic stem cell transplantation

Grube, Matthias; Loeffler, Juergen; Mezger, Markus; Krüger, Bernd; Echtenacher, Bernd; Hoffmann, Petra; Edinger, Matthias; Einsele, Hermann; Andreesen, Reinhard; Holler, Ernst

doi:10.3109/13693786.2013.809630

Public

TLR5 stop codon polymorphism is associated with invasive aspergillosis after allogeneic stem cell transplantation

Published in Medical Mycology • Jul 18, 2013

Authors:

Matthias Grube

Juergen Loeffler

Markus Mezger

Abstract

Single nucleotide polymorphisms (SNPs) have been associated with an increased incidence of invasive aspergillosis (IA) after allogeneic stem cell transplantation (allo-SCT). We analyzed 41 patients with proven/probable IA after allo-SCT for an association of SNPs, within the TLR2, TLR4, TLR5, TLR9, ...

Subject

TLR5

Single-nucleotide polymorphism

SNP

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