Detection of <i>embB306</i> Mutations in Ethambutol-Susceptible Clinical Isolates of <i>Mycobacterium tuberculosis</i> from Northwestern Russia: Implications for Genotypic Resistance Testing

Mokrousov, Igor; Otten, Tatiana; Vyshnevskiy, Boris; Narvskaya, Olga

doi:10.1128/jcm.40.10.3810-3813.2002

Public

Detection of embB306 Mutations in Ethambutol-Susceptible Clinical Isolates of Mycobacterium tuberculosis from Northwestern Russia: Implications for Genotypic Resistance Testing

Published in Journal of Clinical Microbiology • Sep 28, 2002

Authors:

Igor Mokrousov

Tatiana Otten

Boris Vyshnevskiy

Abstract

A total of 183 epidemiologically unlinked Mycobacterium tuberculosis isolates collected in the St. Petersburg area of Russia from 1996 to 2001 were screened for alterations in codon 306 of the embB gene; mutations in this codon are reported to confer resistance to ethambutol (EMB). The embB306 mutat...

Subject

Ethambutol

Mycobacterium tuberculosis

Genotype

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