Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity

Hénégar, Corneliu; Tordjman, Joan; Achard, Vincent; Lacasa, Danièle; Cremer, Isabelle; Guerre-Millo, Michèle; Poitou, Christine; Basdevant, Arnaud; Štich, Vladimír; Viguerie, Nathalie; Langin, Dominique; Bédossa, Pierre; Zucker, Jean‐Daniel; Clément, Karine

doi:10.1186/gb-2008-9-1-r14

Public

Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity

Published in Genome biology • Jan 21, 2008

Authors:

Corneliu Hénégar

Joan Tordjman

Vincent Achard

Abstract

BACKGROUND: Investigations performed in mice and humans have acknowledged obesity as a low-grade inflammatory disease. Several molecular mechanisms have been convincingly shown to be involved in activating inflammatory processes and altering cell composition in white adipose tissue (WAT). However, t...

Subject

Biology

Adipose tissue

Extracellular matrix

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