Mesenchymal stem cells enhance growth and metastasis of colon cancer.

K, Shinagawa; Y, Kitadai; M, Tanaka; T, Sumida; M, Kodama; Y, Higashi; S, Tanaka; W, Yasui; K, Chayama

doi:10.1002/ijc.25440

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Mesenchymal stem cells enhance growth and metastasis of colon cancer.

Shared by NobleBlocks on Nov 1, 2010 • 12:00 AM UTC

Authors:

Shinagawa K

Kitadai Y

Tanaka M

Abstract

Recently, mesenchymal stem cells (MSCs) were reported to migrate to tumor stroma as well as injured tissue. We examined the role of human MSCs in tumor stroma using an orthotopic nude mice model of KM12SM colon cancer. In in vivo experiments, systemically injected MSCs migrated to the stroma of orth...

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