Glycans Are a Novel Biomarker of Chronological and Biological Ages

Krištić, Jasminka; Vučković, Frano; Menni, Cristina; Klarić, Lucija; Keser, Toma; Bečeheli, Ivona; Pučić‐Baković, Maja; Novokmet, Mislav; Mangino, Massimo; Thaqi, Kujtim; Rudan, Pavao; Novokmet, Natalija; Šarac, Jelena; Missoni, Saša; Kolčić, Ivana; Polašek, Ozren; Rudan, Igor; Campbell, Harry; Hayward, Caroline; S. Aulchenko, Yurii; M. Valdes, Ana; F. Wilson, James; Gornik, Olga; Primorac, Dragan; Zoldoš, Vlatka; D. Spector, Tim; Lauc, Gordan

doi:10.1093/gerona/glt190

Public

Glycans Are a Novel Biomarker of Chronological and Biological Ages

Published in The Journals of Gerontology Series A • Dec 10, 2013

Authors:

Jasminka Krištić

Frano Vučković

Cristina Menni

Abstract

Fine structural details of glycans attached to the conserved N-glycosylation site significantly not only affect function of individual immunoglobulin G (IgG) molecules but also mediate inflammation at the systemic level. By analyzing IgG glycosylation in 5,117 individuals from four European populati...

Subject

Glycosylation

Glycan

Biological age

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