Essential Roles of CD8+CD122+ Regulatory T Cells in the Maintenance of T Cell Homeostasis

Rifa’i, Muhaimin; Kawamoto, Yoshiyuki; Nakashima, Izumi; Suzuki, Haruhiko

doi:10.1084/jem.20040395

Public

Essential Roles of CD8+CD122+ Regulatory T Cells in the Maintenance of T Cell Homeostasis

Published in The Journal of Experimental Medicine • Nov 1, 2004

Authors:

Muhaimin Rifa’i

Yoshiyuki Kawamoto

Izumi Nakashima

Abstract

Regulation of immune system is of paramount importance to prevent immune attacks against self-components. Mice deficient in the interleukin (IL)-2/IL-15 receptor beta chain, CD122, are model animals of such immune attacks and characteristically have a high number of abnormally activated T cells. Her...

Subject

Homeostasis

Cytotoxic T cell

Biology

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