Angiogenic Gene Therapy (AGENT) Trial in Patients With Stable Angina Pectoris

L. Grines, Cindy; W. Watkins, Matthew; Helmer, Greg; Penny, William; Brinker, Jeffrey; D. Marmur, Jonathan; West, Andrew; J. Rade, Jeffery; Marrott, Pran; Kirk Hammond, H.; L. Engler, Robert

doi:10.1161/hc1102.105595

Public

Angiogenic Gene Therapy (AGENT) Trial in Patients With Stable Angina Pectoris

Shared by NobleBlocks on Mar 19, 2002 • 12:00 AM UTC

Authors:

Cindy L. Grines

Matthew W. Watkins

Greg Helmer

Abstract

Background — The angiogenic response to myocardial ischemia can be augmented in animal models by gene transfer with the use of a replication defective adenovirus (Ad) containing a human fibroblast growth factor (FGF) gene. Methods and Results — The objectives of the Angiogenic GENe Therapy (AGENT) t...

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