Diagnostic Accuracy of Plasma Glial Fibrillary Acidic Protein for Differentiating Intracerebral Hemorrhage and Cerebral Ischemia in Patients with Symptoms of Acute Stroke

Foerch, Christian; Niessner, Marion; Back, Tobias; Bauerle, Michael; Marco De Marchis, Gian; Ferbert, A.; Grehl, H.; F. Hamann, Gerhard; H. Jacobs, Andréas; Kastrup, Andreas; Klimpe, Sven; Palm, Frederick; Thomalla, Götz; Worthmann, Hans; FAST Study Group, BE; Sitzer, Matthias

doi:10.1373/clinchem.2011.172676

Public

Diagnostic Accuracy of Plasma Glial Fibrillary Acidic Protein for Differentiating Intracerebral Hemorrhage and Cerebral Ischemia in Patients with Symptoms of Acute Stroke

Published in Clinical Chemistry • Nov 29, 2011

Authors:

Christian Foerch

Marion Niessner

Tobias Back

Abstract

BACKGROUND: Glial fibrillary acidic protein (GFAP) is a biomarker candidate indicative of intracerebral hemorrhage (ICH) in patients with symptoms of acute stroke. GFAP is released rapidly in the presence of expanding intracerebral bleeding, whereas a more gradual release occurs in ischemic stroke. ...

Subject

Medicine

Intracerebral hemorrhage

Glial fibrillary acidic protein

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