Clofazimine for the Treatment of Multidrug-Resistant Tuberculosis: Prospective, Multicenter, Randomized Controlled Study in China

Tang, Shenjie; Yao, Lan; Hao, Xiaohui; Liu, Yidian; Zeng, Linhai; Liu, Gang; Li, Mingwu; Li, Fujian; Wu, Meiying; Zhu, Yousheng; Sun, Hua; Gu, Jin; Wang, Xiafang; Zhang, Zhanjun

doi:10.1093/cid/civ027

Public

Clofazimine for the Treatment of Multidrug-Resistant Tuberculosis: Prospective, Multicenter, Randomized Controlled Study in China

Published in Clinical Infectious Diseases • Jan 20, 2015

Authors:

Shenjie Tang

Lan Yao

Xiaohui Hao

Abstract

BACKGROUND: Clofazimine (Cfz) has shown activity against Mycobacterium tuberculosis, including multidrug-resistant (MDR) strains in vitro and in animal studies. Here we evaluate the clinical efficacy and tolerability of using Cfz to treat MDR tuberculosis in China. METHODS: We enrolled 105 patients ...

Subject

Clofazimine

Medicine

Tolerability

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