Malignant peripheral nerve sheath tumours in neurofibromatosis 1

Gareth Evans, D.; E Baser, M; McGaughran, J; Sharif, S; Howard, E; Moran, A

doi:10.1136/jmg.39.5.311

Public

Malignant peripheral nerve sheath tumours in neurofibromatosis 1

Published in Journal of Medical Genetics • May 1, 2002

Authors:

D. Gareth Evans

M E Baser

J McGaughran

Abstract

BACKGROUND: Cross sectional studies have shown that 1-2% of patients with neurofibromatosis 1 (NF1) develop malignant peripheral nerve sheath tumours (MPNST). However, no population based longitudinal studies have assessed lifetime risk. METHODS: NF1 patients with MPNST were ascertained from two sou...

Subject

Neurofibromatosis

Medicine

Malignant peripheral nerve sheath tumor

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