Photochemical inactivation of viruses and bacteria in platelet concentrates by use of a novel psoralen and long-wavelength ultraviolet light.

Lin, L; N Cook, D; P Wiesehahn, G; Alfonso, R; Behrman, B; D Cimino, G; Corten, L; B Damonte, P; Dikeman, R; Dupuis, K; M Fang, Y; V Hanson, C; E Hearst, J; Y Lin, C; F Londe, H; Metchette, K; T Nerio, A; T Pu, J; A Reames, A; Rheinschmidt, M; Tessman, J; T Isaacs, S; Wollowitz, S; Corash, L

doi:10.1046/j.1537-2995.1997.37497265344.x

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Photochemical inactivation of viruses and bacteria in platelet concentrates by use of a novel psoralen and long-wavelength ultraviolet light.

Shared by NobleBlocks on Apr 1, 1997 • 12:00 AM UTC

Authors:

L Lin

D N Cook

G P Wiesehahn

Abstract

BACKGROUND: A photochemical treatment process has been developed for the inactivation of viruses and bacteria in platelet concentrates. This process is based on the photochemical reaction of a novel psoralen, S-59, with nucleic acids upon illumination with long-wavelength ultraviolet light (UVA, 320...

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