Photochemical inactivation of viruses and bacteria in platelet concentrates by use of a novel psoralen and long‐wavelength ultraviolet light

Lin, L.; N. Cook, David; Wiesehahn, Gary; Alfonso, R.; Behrman, B.; D. Cimino, George; Corten, L.; Damonte, Patrizia; Dikeman, R.; Dupuis, Kent; Fang, Yiming; V. Hanson, Carl; Hearst, J; Lin, Chih-Pei; F. Londe, H.; Metchette, Ken; T. Nerio, A.; Pu, Juan; Reames, Aaron; Rheinschmidt, Margaret; W. Tessman, John; T. Isaacs, Stephen; Wollowitz, S.; Corash, Laurence

doi:10.1046/j.1537-2995.1997.37497265344.x

Public

Photochemical inactivation of viruses and bacteria in platelet concentrates by use of a novel psoralen and long‐wavelength ultraviolet light

Published in Transfusion • Apr 1, 1997

Authors:

L. Lin

David N. Cook

Gary Wiesehahn

Abstract

BACKGROUND: A photochemical treatment process has been developed for the inactivation of viruses and bacteria in platelet concentrates. This process is based on the photochemical reaction of a novel psoralen, S-59, with nucleic acids upon illumination with long-wavelength ultraviolet light (UVA, 320...

Subject

Infectivity

Virus

Platelet

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