Phase III Study Comparing Cisplatin Plus Fluorouracil to Paclitaxel, Cisplatin, and Fluorouracil Induction Chemotherapy Followed by Chemoradiotherapy in Locally Advanced Head and Neck Cancer

Hitt, Ricardo; López–Pousa, Antonio; Martínez‐Trufero, Javier; Javier Escrig, V.; Carles, Joan; Rizo, Alfredo; Isla, Dolores; Eugenia Vega, M.; Luis Gomez Marti, Juan; S. N. Lobo, Francisco; Pastor, Pedro; Valentí, Vicente; Belón, Joaquín; A. Sánchez, Miguel; Chaib, C.; Pallarés, Cinta; Antón, Antonio; Cervantes, Andrés; Paz‐Ares, Luis; Cortés-Funes, H.

doi:10.1200/jco.2004.00.1990

Public

Phase III Study Comparing Cisplatin Plus Fluorouracil to Paclitaxel, Cisplatin, and Fluorouracil Induction Chemotherapy Followed by Chemoradiotherapy in Locally Advanced Head and Neck Cancer

Published in Journal of Clinical Oncology • Nov 8, 2005

Authors:

Ricardo Hitt

Antonio López–Pousa

Javier Martínez‐Trufero

Abstract

PURPOSE: To compare the antitumor activity and toxicity of the two induction chemotherapy treatments of paclitaxel, cisplatin, and fluorouracil (FU; PCF) versus standard cisplatin and FU (CF), both followed by chemoradiotherapy (CRT), in locally advanced head and neck cancer (HNC). PATIENTS AND METH...

Subject

Fluorouracil

Cisplatin

Medicine

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