Chemerin inhibits IGF-1-induced progesterone and estradiol secretion in human granulosa cells

Reverchon, Maxime; Cornuau, Marion; Ramé, Christelle; Guérif, Fabrice; Royère, Dominique; Dupont, Joëlle

doi:10.1093/humrep/des089

Public

Chemerin inhibits IGF-1-induced progesterone and estradiol secretion in human granulosa cells

Published in Human Reproduction • Mar 23, 2012

Authors:

Maxime Reverchon

Marion Cornuau

Christelle Ramé

Abstract

BACKGROUND: Chemerin is a novel adipokine involved in the regulation of adipocyte development, inflammation and metabolic functions. To date, no role of this adipokine in reproductive functions has been described. In the present study, we identified chemerin and its receptor, CMKLR1 (chemokine-like ...

Subject

Chemerin

Endocrinology

Internal medicine

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