SIFT web server: predicting effects of amino acid substitutions on proteins

Sim, Ngak-Leng; Naresh Kumar, P.; Hu, Jing; Henikoff, Steven; Schneider, Georg; C. Ng, Pauline

doi:10.1093/nar/gks539

Public

SIFT web server: predicting effects of amino acid substitutions on proteins

Published in Nucleic Acids Research • Jun 9, 2012

Authors:

Ngak-Leng Sim

P. Naresh Kumar

Jing Hu

Abstract

The Sorting Intolerant from Tolerant (SIFT) algorithm predicts the effect of coding variants on protein function. It was first introduced in 2001, with a corresponding website that provides users with predictions on their variants. Since its release, SIFT has become one of the standard tools for cha...

Subject

Scale-invariant feature transform

Indel

Biology

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