Monitoring plasma HIV-1 RNA levels in addition to CD4+ lymphocyte count improves assessment of antiretroviral therapeutic response. ACTG 241 Protocol Virology Substudy Team.

MD, Hughes; VA, Johnson; MS, Hirsch; JW, Bremer; T, Elbeik; A, Erice; DR, Kuritzkes; WA, Scott; SA, Spector; N, Basgoz; MA, Fischl; RT, D'Aquila

doi:10.7326/0003-4819-126-12-199706150-00001

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Monitoring plasma HIV-1 RNA levels in addition to CD4+ lymphocyte count improves assessment of antiretroviral therapeutic response. ACTG 241 Protocol Virology Substudy Team.

Shared by NobleBlocks on Jun 1, 1997 • 12:00 AM UTC

Authors:

Hughes MD

Johnson VA

Hirsch MS

Abstract

Background CD4+ lymphocyte counts and plasma HIV-1 RNA levels predict progression of HIV-related disease, but the relative importance of these and other virological factors in defining response to antiretroviral therapy is not yet clear.Objective To determine the short-term variability of plasma HIV...

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