Diketopyrrolopyrrole‐Porphyrin Conjugates with High Two‐Photon Absorption and Singlet Oxygen Generation for Two‐Photon Photodynamic Therapy

Schmitt, Julie; Heitz, Valérie; Sour, Angélique; Bolze, Frédéric; Ftouni, Hussein; Nicoud, Jean‐François; Flamigni, Lucia; Ventura, Barbara

doi:10.1002/anie.201407537

Public

Diketopyrrolopyrrole‐Porphyrin Conjugates with High Two‐Photon Absorption and Singlet Oxygen Generation for Two‐Photon Photodynamic Therapy

Published in Angewandte Chemie International Edition • Nov 4, 2014

Authors:

Julie Schmitt

Valérie Heitz

Angélique Sour

Abstract

Two-photon photodynamic therapy is a promising therapeutic method which requires the development of sensitizers with efficient two-photon absorption and singlet-oxygen generation. Reported here are two new diketopyrrolopyrrole-porphyrin conjugates as robust two-photon absorbing dyes with high two-ph...

Subject

Photodynamic therapy

Singlet oxygen

Phototoxicity

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