Clinical Features and Outcome of Patients With Non–Small-Cell Lung Cancer Who Harbor <i>EML4-ALK</i>

T. Shaw, Alice; Y. Yeap, Beow; Mino–Kenudson, Mari; R. Digumarthy, Subba; B. Costa, Daniel; S. Heist, Rebecca; Solomon, Benjamin; Stubbs, Hannah; Admane, Sonal; McDermott, Ultan; Settleman, Jeffrey; Kobayashi, Susumu; J. Mark, Eugene; J. Rodig, Scott; R. Chirieac, Lucian; L. Kwak, Eunice; J. Lynch, Thomas; John Iafrate, A.

doi:10.1200/jco.2009.22.6993

Public

Clinical Features and Outcome of Patients With Non–Small-Cell Lung Cancer Who Harbor EML4-ALK

Published in Journal of Clinical Oncology • Aug 10, 2009

Authors:

Alice T. Shaw

Beow Y. Yeap

Mari Mino–Kenudson

Abstract

PURPOSE: The EML4-ALK fusion oncogene represents a novel molecular target in a small subset of non-small-cell lung cancers (NSCLC). To aid in identification and treatment of these patients, we examined the clinical characteristics and treatment outcomes of patients who had NSCLC with and without EML...

Subject

Medicine

KRAS

Lung cancer

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