A Placebo-Controlled Trial of Oral Cladribine for Relapsing Multiple Sclerosis

Giovannoni, Gavin; Comı, Gıancarlo; D. Cook, Stuart; Rammohan, Kottil; Rieckmann, Peter; Soelberg Sørensen, Per; Vermersch, Patrick; Chang, Peter; Hamlett, Anthony; Musch, Bruno; J. Greenberg, Steven

doi:10.1056/nejmoa0902533

Public

A Placebo-Controlled Trial of Oral Cladribine for Relapsing Multiple Sclerosis

Published in New England Journal of Medicine • Jan 20, 2010

Authors:

Gavin Giovannoni

Gıancarlo Comı

Stuart D. Cook

Abstract

BACKGROUND: Cladribine provides immunomodulation through selective targeting of lymphocyte subtypes. We report the results of a 96-week phase 3 trial of a short-course oral tablet therapy in patients with relapsing-remitting multiple sclerosis. METHODS: We randomly assigned 1326 patients in an appro...

Subject

Cladribine

Medicine

Multiple sclerosis

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!