A pilot study of rapid benchtop sequencing of Staphylococcus aureus and Clostridium difficile for outbreak detection and surveillance

W. Eyre, David; Golubchik, Tanya; Claire Gordon, N; Bowden, Rory; Piazza, Paolo; M. Batty, Elizabeth; L. C. Ip, Camilla; J. Wilson, Daniel; Didelot, Xavier; O’Connor, Lily; Lay, Rochelle; Buck, David; Kearns, Angela; Shaw, Angela; R. Paul, John; H. Wilcox, Mark; Donnelly, Peter; Peto, Tim; Walker, Andrew; W. Crook, Derrick

doi:10.1136/bmjopen-2012-001124

Public

A pilot study of rapid benchtop sequencing of Staphylococcus aureus and Clostridium difficile for outbreak detection and surveillance

Published in BMJ Open • Jan 1, 2012

Authors:

David W. Eyre

Tanya Golubchik

N Claire Gordon

Abstract

OBJECTIVES: To investigate the prospects of newly available benchtop sequencers to provide rapid whole-genome data in routine clinical practice. Next-generation sequencing has the potential to resolve uncertainties surrounding the route and timing of person-to-person transmission of healthcare-assoc...

Subject

Medicine

Clostridium difficile

Outbreak

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