HIV-1 Protease Mutations and Protease Inhibitor Cross-Resistance

Rhee, Soo‐Yon; Taylor, Jonathan; Jeffrey Fessel, W.; R. Kaufman, David; Towner, William; Troia, Paolo; Ruane, Peter; Hellinger, James; Shirvani, Vivian; Zolopa, Andrew; W. Shafer, Robert

doi:10.1128/aac.00574-10

Public

HIV-1 Protease Mutations and Protease Inhibitor Cross-Resistance

Published in Antimicrobial Agents and Chemotherapy • Jul 27, 2010

Authors:

Soo‐Yon Rhee

Jonathan Taylor

W. Jeffrey Fessel

Abstract

The effects of many protease inhibitor (PI)-selected mutations on the susceptibility to individual PIs are unknown. We analyzed in vitro susceptibility test results on 2,725 HIV-1 protease isolates. More than 2,400 isolates had been tested for susceptibility to fosamprenavir, indinavir, nelfinavir, ...

Subject

Nelfinavir

Darunavir

Lopinavir

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!