Genome-Wide Expression Profiling Identifies Type 1 Interferon Response Pathways in Active Tuberculosis

H. M. Ottenhoff, Tom; Hari Dass, Ranjeeta; Yang, Ninghan; M. Zhang, Mingzi; E. E. Wong, Hazel; Sahiratmadja, Edhyana; Chuen Khor, Chiea; Alisjahbana, Bachti; van Crevel, Reinout; Marzuki, Sangkot; Seielstad, Mark; van de Vosse, Esther; L. Hibberd, Martin

doi:10.1371/journal.pone.0045839

Public

Genome-Wide Expression Profiling Identifies Type 1 Interferon Response Pathways in Active Tuberculosis

Published in PLoS ONE • Sep 21, 2012

Authors:

Tom H. M. Ottenhoff

Ranjeeta Hari Dass

Ninghan Yang

Abstract

Tuberculosis (TB), caused by Mycobacterium tuberculosis (M.tb), remains the leading cause of mortality from a single infectious agent. Each year around 9 million individuals newly develop active TB disease, and over 2 billion individuals are latently infected with M.tb worldwide, thus being at risk ...

Subject

Interferon

Tuberculosis

Mycobacterium tuberculosis

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